Clinical health publishing

All Articles

Written by licensed PharmDs, reviewed by practicing physicians. No ads disguised as content. No SEO fluff.

Featured

GLP-1s 12 min read

Retatrutide: The Most Hyped Weight Loss Drug You Can't Legally Have Yet

Retatrutide's Phase 2 data showed 24% weight loss — more than any approved GLP-1 drug. It's also not FDA-approved, can't be legally compounded, and is being sold at med spas anyway. A PharmD explains the science, the hype, and why you should wait.

SM
Sean Moshrefi, PharmD, MS · Reviewed by Shant Pezeshkian, DO, MPH
Biomarkers 12 min read

What Is ApoB and Why It Matters More Than LDL

LDL cholesterol is the most commonly cited cardiovascular risk marker — and one of the least accurate. A PharmD explains why ApoB is a superior measure of atherogenic risk, how discordance works, and what your target should be.

SM
Sean Moshrefi, PharmD, MS
Lab Testing 14 min read

Best Direct-to-Consumer Lab Testing Companies — A PharmD Review

A PharmD compares the best direct-to-consumer lab testing companies — Function Health, Ulta Lab Tests, Inside Tracker, Everlywell, and more — on biomarker coverage, accuracy, cost, and clinical usefulness.

SM
Sean Moshrefi, PharmD, MS
GLP-1s 12 min read

Compounded GLP-1s Are Being Banned — What California Patients Need to Know Right Now

The FDA has ended the legal basis for compounded semaglutide and tirzepatide, and major telehealth platforms have already exited the market. A California PharmD explains the regulatory timeline, what it means for patients mid-treatment, and what your real options are right now.

SM
Sean Moshrefi, PharmD, MS
GLP-1s 15 min read

Compounded Semaglutide vs. Ozempic: A Pharmacist's Honest Assessment

A licensed pharmacist breaks down the real clinical differences between compounded semaglutide and brand-name Ozempic — bioequivalence, safety, the salt form question, and a framework for evaluating your source.

SM
Sean Moshrefi, PharmD, MS
Biomarkers 13 min read

HOMA-IR Explained: How to Measure Insulin Resistance at Home

HOMA-IR is the most practical way to detect insulin resistance years before diabetes develops. A PharmD explains the formula, what the numbers mean, how to order the test yourself, and what to do if your score is high.

SM
Sean Moshrefi, PharmD, MS
Metabolic Health 11 min read

hsCRP: The Inflammation Marker That Connects Metabolic Disease to Heart Attacks

High-sensitivity CRP is one of the most underused metabolic risk markers in primary care. A PharmD explains what hsCRP measures, how it connects insulin resistance to cardiovascular disease, and what actually moves the number.

SM
Sean Moshrefi, PharmD, MS
Biomarkers 12 min read

Lp(a): The Cardiovascular Risk Factor Your Doctor Probably Never Tested

Lipoprotein(a) — or Lp(a) — is a genetically inherited cardiovascular risk factor that affects 1 in 5 people and is almost never ordered by primary care. A PharmD breaks down what it is, how to test it, and what to do about it.

SM
Sean Moshrefi, PharmD, MS
GLP-1s 13 min read

Mounjaro vs. Ozempic: Beyond the Marketing

Ozempic and Mounjaro dominate headlines, but most coverage misses the clinical substance. A PharmD breaks down semaglutide vs. tirzepatide on mechanism, efficacy, cardiovascular outcomes data, side effects, and who each drug is actually best for.

SM
Sean Moshrefi, PharmD, MS
Longevity 12 min read

NAD+ Precursors (NMN & NR): A PharmD Separates the Hype from the Evidence

NMN and NR supplements are everywhere in longevity circles. A PharmD reviews the actual human clinical trial data on NAD+ precursors — what they do, what the evidence shows, and whether they're worth taking.

SM
Sean Moshrefi, PharmD, MS
Longevity 15 min read

Peptide Therapy for Longevity: A PharmD's Honest Breakdown of What Works, What Doesn't, and What's Hype

Peptides like BPC-157, CJC-1295, sermorelin, and TB-500 are everywhere in longevity circles. A PharmD cuts through the noise with honest evidence grades, regulatory context, and a framework for thinking about peptide therapy in 2026.

SM
Sean Moshrefi, PharmD, MS
GLP-1s 14 min read

What Nobody Tells You About Stopping Semaglutide

What actually happens when you stop taking Ozempic or Wegovy — the weight regain data, the physiology behind it, discontinuation symptoms, and what a clinical pharmacist recommends before you stop.

SM
Sean Moshrefi, PharmD, MS
Biomarkers 13 min read

Your Doctor Said Your Cholesterol Is Fine. Here's Why They Might Be Wrong.

Standard cholesterol panels miss the biomarkers that actually predict cardiovascular risk. A clinical pharmacist explains ApoB, Lp(a), and why a normal LDL-C does not mean your cardiovascular risk is under control.

SM
Sean Moshrefi, PharmD, MS