Evidence-based articles and PharmD-curated supplement protocols — covering GLP-1 therapy, advanced biomarkers, insulin resistance, hormone therapy, supplement stacks, and longevity. Every word written by a licensed PharmD and reviewed by a practicing physician, at the clinical depth your doctor doesn't have time to explain.
Supplement Protocols
PharmD-curated stacks for your health goals
Protocols
HOMA-IR
Measure and reverse insulin resistance
Metabolic Health
ApoB & Lp(a)
The lipid markers your standard panel misses
Biomarkers
GLP‑1 Therapy
Ozempic, Wegovy, Mounjaro — clinical depth
GLP‑1 Medications
Ask a pharmacist
We're building a pharmacist Q&A service for the questions your doctor doesn't have time for — drug interactions, biomarker interpretation, GLP-1 dose adjustments, and more. Join the waitlist for early access.
✓ You're on the list — we'll reach out when it launches.
Health tools
Enter a value from your blood work and see which clinical range it falls into — every threshold drawn from the guideline it cites. Or build the panel worth asking for before you get tested.
Start here
Our current pick, alongside the two most recently reviewed pieces.
Latest analysis
In 2002 the Women's Health Initiative frightened a generation off hormone therapy. In November 2025 the FDA began stripping the warnings back off. What the trial actually found, what the timing hypothesis does and doesn't prove, and how to think about risk in 2026.
Two large trials tested nearly identical omega-3 doses and reached opposite conclusions. Why they disagree, what the mineral oil placebo controversy means, and whether the fish oil in your cabinet does anything.
Supplement protocols
Our articles tell you the science. Our protocols weigh the options: PharmD-curated, physician-reviewed shortlists with specific doses, evidence tiers, and drug-interaction analysis — so you can choose what's worth taking, not swallow a fistful of pills.
The supplements with the strongest evidence for people on semaglutide or tirzepatide — muscle preservation, nutrient repletion, GI tolerance, and metabolic support, with specific doses and evidence levels.
Why PrecisionOptimize
Our articles are written from scratch by licensed PharmDs — not ghostwritten by content agencies and rubber-stamped by a consultant. The pharmacist who signs the article wrote every word.
Drug-drug interactions. Pharmacokinetics. Why your ApoB matters more than your LDL-C. The stuff that takes a clinical education to explain clearly — and the patience to do it without dumbing it down.
We're building toward direct clinical services — consultations, lab ordering, and GLP-1 prescribing for California patients. In the meantime, our content gives you the clinical depth to have better conversations with your own provider.
How we compare
| Feature | Content farms | Telehealth apps | PrecisionOptimize |
|---|---|---|---|
| Written by pharmacists | ✗ | ✗ | ✓ |
| Physician reviewed | Sometimes | ✗ | ✓ |
| Drug interaction detail | ✗ | ✗ | ✓ |
| Interactive lab tools | Basic | ✗ | ✓ |
| Clinical services | ✗ | ✓ | Soon |
| Affiliate transparency | Rarely | N/A | ✓ |
| Free to read | ✓ | ✗ | ✓ |
Clinical services
Metabolic Health Consultation
GLP-1 prescribing, physician supervised
Advanced Lab Panel
ApoB, Lp(a), HOMA-IR + interpretation
PharmD Lab Report
Upload your labs, get a clinical summary
Medication Review
Drug interactions + optimization
Clinical services launching soon
Articles are free to read in the meantime
Our team
Clinical Pharmacist & Author
Licensed pharmacist based in California. PharmD from UCSF, MS in Regulatory Sciences from USC. Expertise in medical writing and drug information for healthcare professionals and patients.
Medical Director & Reviewer
Emergency medicine physician in Los Angeles, CA, affiliated with Baylor St. Luke's and Cedars-Sinai. DO from Midwestern University, MPH from Loma Linda University. Emergency Medicine Fellowship at Baylor College of Medicine.
Every article is free. Written by licensed PharmDs, reviewed by physicians, and built for people who want real clinical depth — no fluff, no filler.