PharmD-graded supplement reviews
Honest, evidence-graded reviews of individual supplements — what the human data actually shows, the dose that matters, and whether it's worth your money. Each review is written by a licensed pharmacist and reviewed by a physician.
Berberine is trending as "nature's Ozempic." What the human evidence actually shows on blood sugar, cholesterol, and weight — and why it's no substitute for GLP‑1 drugs.
Creatine is the most studied sports supplement on earth — but the newest research is about the brain. The human evidence on creatine for cognition, memory, and menopause, and what dose actually has data behind it.
The form on the label matters more than the milligrams. Why a normal magnesium blood test doesn't rule out a shortfall, which forms are absorbed and which aren't, and what the evidence actually supports.
NMN and NR supplements are everywhere in longevity circles. The actual human clinical trial data on NAD+ precursors — what they do, what the evidence shows, and whether they're worth taking.
Two large trials tested nearly identical omega-3 doses and reached opposite conclusions. Why they disagree, what the mineral oil placebo controversy means, and whether the fish oil in your cabinet does anything.
Vitamin D was supposed to prevent cancer, heart disease, diabetes, and fractures. Then the randomized trials reported. What they actually found, why the 30 ng/mL target was never validated, and who still genuinely needs testing.
Sleep specialists recommend against melatonin for chronic insomnia, and one analysis found supplement content ranging from 83% below label to nearly five times above it. An honest ranking of melatonin, glycine, L-theanine, and apigenin.
Nattokinase, an enzyme from fermented soy (natto), is marketed as a natural clot-buster for heart health. Separating the real fibrinolytic science from the supplement hype — and the bleeding risks.
Longevity 'stacks' now run to dozens of pills a day. An audit of the supplement cabinet — what the large trials actually show, what's redundant, what carries real risk, and how to build a shorter, smarter list.
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Tackling a whole goal?
Our supplement protocols line up the individually-reviewed compounds worth considering for one goal — with doses, evidence tiers, and drug-interaction notes, so you can pick what fits rather than take everything.